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Category: Update in fertility research

Should I test my embryos for BRCA gene mutation during my IVF cycle?

A recent announcement by Angelina Jolie has brought attention to BRCA gene mutation again and the increased risk of developing breast and ovarian cancer. She announced her “double mastectomy” to minimize the risk of developing breast cancer in the future. In the near future, she will also announce removal of her ovaries to minimize the […]

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Is amniocentesis becoming obsolete for Down’s syndrome screening?

A recently developed test called the Materni21 allows non-invasive screening for Down’s syndrome during early pregnancy simply from a blood draw from the mother. The test is being evaluated further by clinical trials for its reliability and accuracy, but the initial studies report promising results. It appears that fetal DNA is detectable in the maternal […]

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Prevention of OHSS in patients with PCOS undergoing IVF

Patients with ovarian hyperstimulation syndrome (OHSS) typically present with ovarian distention, pelvic pressure and fluid build-up in the pelvic area commonly associated with ovarian stimulation or In Vitro Fertilization (IVF). Whereas most cases of OHSS are mild in nature, 1-2% of the time symptoms can be severe, limiting activity, requiring pain management and even hospitalization. […]

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Tubal Reversal: One or Both Tubes?

It is considered ideal if both tubes are re-connected (bilateral re-anastomosis) during tubal reversal surgery, but in some cases this may not be possible. Patients with a history of unilateral salpingectomy (removal of one of the fallopian tubes), one sided tubal damage or with a blocked tube, very short tubal segment, unilateral salpingo-oophorectomy (removal of […]

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Dilatation and Curettage

Dilation and curettage (D and C or D&C) is a minor gynecological procedure commonly used to diagnose and treat abnormal bleeding from the uterus or to remove unhealthy tissue if a woman has a miscarriage. It can also be used to diagnose uterine cancer or precancerous cells (endometrial hyperplasia) by removing the endometrial cells for […]

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Immunological Implantation Failure and Immune Treatment for Infertility and IVF

Currently, with few exceptions, practitioners of assisted reproduction tend to attribute “unexplained and/or repeated” IVF failure(s), almost exclusively to poor embryo quality, advocating adjusted protocols for ovarian stimulation and/or gamete and embryo preparation as a potential remedy. The idea that having failed IVF, all that it takes to ultimately succeed is to keep trying over […]

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Thrombophilias or Clotting Disorders

Thrombophilias are inherited or acquired conditions, which predispose an individual to thromboembolism (blood clots). This is due to an imbalance between certain blood clotting factors and anti-clotting proteins in the blood. As many as one in five people in the United States is a carrier of a type of thrombophilia. There is limited information in […]

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Dr. Bayrak Announces Milestone Birth in Southern California from Genetically Tested Frozen Egg

I am excited to announce the birth of the first baby in Southern California early this week as a result of In Vitro Fertilization (IVF) using a genetically tested and frozen egg by comparative genomic hybridization (CGH) (See the announcement at www.prnewswire.com) After treating the first CGH cases in Southern California with IVF for infertility, I […]

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Update on MTHFR, Thrombophilias & IVF

There has been confusion over the years about testing for clotting disorders in infertility patients, especially those undergoing IVF treatment. Routine testing for these disorders is not recommended as a part of the initial work up for infertility and prior to or during pregnancy. Unfortunately, there have been overutilization and overinterpretation of these tests (thrombophilia […]

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The Embryo Marker Tests, CGH and IVF

Embryo marker tests have been developed over the years in IVF practices to identify the best embryos for transfer into the uterus, but no test has been found to be 100% reliable. Conventional approach in selecting the better quality embryos still relies on the appearance of the embryos under the microscope by paying attention to […]

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